Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells

Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer

Herbert I. Hurwitz, Louis Fehrenbacher, William Novotny et al. · New England Journal of Medicine · 2004 · 10.9K citations · Full text

Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

J-Y Douillard, David Cunningham, AD Roth et al. · The Lancet · 2000 · 3.3K citations

Medicine, Pharmacology, Colorectal Cancer +6

Irinotecan plus Fluorouracil and Leucovorin for Metastatic Colorectal Cancer

Leonard B. Saltz, John V. Cox, Charles D. Blanke et al. · New England Journal of Medicine · 2000 · 3K citations · Full text

CpG island methylator phenotype in colorectal cancer

Minoru Toyota, Nita Ahuja, Mutsumi Ohe-Toyota et al. · Proceedings of the National Academy of Sciences · 1999 · 2.5K citations

Tumor Biology, Aberrant Methylation, Medicine +12

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

M Sawadogo · Cell · 1985 · 1.2K citations

Transcriptional Regulation, Natural Sciences, Genetics +11