Facile synthesis of alkyl β-benzyloxyaminocarboxyolates related to monocyclic β-lactams.

Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria

R. B. Sykes, D P Bonner, Karen Bush et al. · Antimicrobial Agents and Chemotherapy · 1982 · 311 citations

Life Sciences, Microbiology, Pharmacology +12

Synthesis of .beta.-lactams from substituted hydroxamic acids

Marvin J. Miller, Phillip G. Mattingly, M. A. MORRISON et al. · Journal of the American Chemical Society · 1980 · 147 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

Titanium trichloride reduction of substituted N-hydroxy-2-azetidinones and other hydroxamic acids

Phillip G. Mattingly, Marvin J. Miller · The Journal of Organic Chemistry · 1980 · 117 citations

Natural Sciences, Chemistry, Analytical Chemistry +4

New and effective route to β-lactams. The reaction of ketene silyl acetals with schiff bases promoted by titanium tetrachloride

Iwao Ojima, Shin‐ichi Inaba, Katsuhiko Yoshida · Tetrahedron Letters · 1977 · 110 citations

Pharmacy, Chemistry, Medicinal Chemistry +7

Monobactams. Preparation of (S)-3-amino-2-oxoazetidine-1-sulfonic acids from L-.alpha.-amino-.beta.-hydroxy acids via their hydroxamic esters

David Floyd, A. W. FRITZ, J. PLUSCEC et al. · The Journal of Organic Chemistry · 1982 · 102 citations

Natural Sciences, Biochemistry, Chemistry +6