Inhibition of endothelial adhesion molecule expression by <i>Monascus purpureus</i>‐fermented rice metabolites, monacolin K, ankaflavin, and monascin

Chih-Pei Lin, Yun-Lian Lin, Po‐Hsun Huang, Hui-Szu Tsai, Yung‐Hsiang Chen

Journal of the Science of Food and Agriculture · 2011 · 66 citations · 34 references

Abstract

Monascus-fermented rice metabolites reduced TNF-α-stimulated endothelial adhesiveness as well as downregulating intracellular ROS formation, NF-κB activation, and VCAM-1/E-selectin expression in HAECs, supporting the notion that the various metabolites from Monascus-fermented rice might have potential implications in clinical atherosclerosis disease.

References

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