Concepedia
Journal of Pharmacological and Toxicological Methods · 1999 · 32 citations · 16 references
MedicinePharmacologyDrug DesignDrug DiscoveryDrug ReceptorsDrug-receptor InteractionsLigand BindingReceptor BindingReceptor ModelingReceptor-ligand InteractionsConstitutive Androstane Receptor SignalingConstitutive Receptor Activity
16
A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.
Philippe Samama, Susanna Cotecchia, Tommaso Costa et al. · Journal of Biological Chemistry · 1993 · 1.3K citations · Full text
Life Sciences, Molecular Biology, Pharmacology +17
Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins.
Tommaso Costa, A. Herz · Proceedings of the National Academy of Sciences · 1989 · 530 citations · Full text
Medicine, Molecular Biology, Pharmacology +15
Constitutively active 5-hydroxytryptamine2C receptors reveal novel inverse agonist activity of receptor ligands.
E L Barker, Ryan S. Westphal, Dennis E. Schmidt et al. · Journal of Biological Chemistry · 1994 · 257 citations · Full text
Medicine, Biochemistry, Pharmacology +17
The Cubic Ternary Complex Receptor-Occupancy Model III. Resurrecting Efficacy
Jack M. Weiss, Paul H. Morgan, Michael W. Lutz et al. · Journal of Theoretical Biology · 1996 · 211 citations
Medicine, Medicinal Chemistry, Pharmacology +10
The Cubic Ternary Complex Receptor–Occupancy Model I. Model Description
Jack M. Weiss, Paul H. Morgan, Michael W. Lutz et al. · Journal of Theoretical Biology · 1996 · 197 citations
Medicine, Pharmacology, Biomolecular Modeling +11