Concepedia

A novel benzimidazole analogue inhibits the hypoxia-inducible factor (HIF)-1 pathway

Misun Won, Namhui Im, Soo-Hyun Park, Shanthaveerappa K. Boovanahalli, Yinglan Jin, Xuejun Jin, Kyung‐Sook Chung, Moorim Kang, Kiho Lee, Kiho Lee,

Biochemical and Biophysical Research Communications · 2009 · 56 citations · 29 references

DOI

Concepts

References

29

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang et al. · Nature · 1999 · 5.2K citations

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Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

Peter Carmeliet, Yuval Dor, Jean-Marc Herbert et al. · Nature · 1998 · 2.5K citations

, , +16

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.

Gregg L. Semenza, G.L. Wang · Molecular and Cellular Biology · 1992 · 2.4K citations · Full text

, , +17

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases.

Hua Zhong, Angelo M. De Marzo, Erik Laughner et al. · PubMed · 1999 · 2.2K citations

, , +14

Purification and Characterization of Hypoxia-inducible Factor 1

Guang L. Wang, Gregg L. Semenza · Journal of Biological Chemistry · 1995 · 2.1K citations · Full text

, , +14