Concepedia

Pharmacokinetic-pharmacodynamic modeling of drug-induced effect on the QT interval in conscious telemetered dogs

Anna Ollerstam, Sandra A. G. Visser, Anna Persson, Göran Eklund, Lars B. Nilsson, Tomas Forsberg, Stig Johan Wiklund, Johan Gabrielsson, Göran Duker, Ahmad Al‐Saffar

Journal of Pharmacological and Toxicological Methods · 2005 · 49 citations · 25 references

DOI

Concepts

References

25

Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to <i>d</i>‐tubocurarine

Lewis B. Sheiner, Donald R. Stanski, Samuel Vožeh et al. · Clinical Pharmacology & Therapeutics · 1979 · 1.1K citations

, , +17

Relation between QT and RR intervals is highly individual among healthy subjects: implications for heart rate correction of the QT interval

Marek Malík · Heart · 2002 · 441 citations · Full text

, , +13

Problems of Heart Rate Correction in Assessment of Drug‐Induced QT Interval Prolongation

Marek Malik · Journal of Cardiovascular Electrophysiology · 2001 · 279 citations

, , +16

Rate of increase in the plasma concentration of nifedipine as a major determinant of its hemodynamic effects in humans

C. H. Kleinbloesem, P. van Brummelen, Meindert Danhof et al. · Clinical Pharmacology & Therapeutics · 1987 · 178 citations

, , +14

The Antipsychotic Agent Sertindole is a High Affinity Antagonist of the Human Cardiac Potassium Channel HERG

David Rampe, Michael Murawsky, Eric Lewis · Journal of Pharmacology and Experimental Therapeutics · 1998 · 175 citations

, , +15