Use of synthetic peptides in the production and characterization of antibodies directed against predetermined specificities in rat immunoglobulin E

<b>Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide</b>

R. B. Merrifield · Journal of the American Chemical Society · 1963 · 7.6K citations

Natural Sciences, Biochemistry, Chemistry +6

Coupling of enzymes to proteins with glutaraldehyde

Stratis Avraméas · Immunochemistry · 1969 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +6

Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence

James L. Bittle, Richard A. Houghten, Hannah Alexander et al. · Nature · 1982 · 817 citations

Life Sciences, Immunology, Infectious Diseases +13

The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein

John A. Tainer, Elizabeth D. Getzoff, Hannah Alexander et al. · Nature · 1984 · 481 citations

Life Sciences, Biochemistry, Immunology +11

Chemically synthesized peptides predicted from the nucleotide sequence of the hepatitis B virus genome elicit antibodies reactive with the native envelope protein of Dane particles.

Richard A. Lerner, N. Green, Hannah Alexander et al. · Proceedings of the National Academy of Sciences · 1981 · 412 citations · Full text

Life Sciences, Immunology, Molecular Biology +14