Palmitoylation of the C-terminal fragment of p75NTR regulates death signaling and is required for subsequent cleavage by γ-secretase

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High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

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Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons

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Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts

Robert Ehehalt, Patrick Keller, Christian Haass et al. · The Journal of Cell Biology · 2003 · 1.1K citations · Full text

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Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

Kuo‐Fen Lee, En Li, L. Julie Huber et al. · Cell · 1992 · 962 citations

Medicine, Neurobiology, Neuroscience +14