SSR149415, a non-peptide vasopressin V1b receptor antagonist, has long-lasting antidepressant effects in the olfactory bulbectomy-induced hyperactivity depression model

Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V _1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders

Guy Griebel, Jacques Simiand, Claudine Serradeil‐Le Gal et al. · Proceedings of the National Academy of Sciences · 2002 · 462 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Blockade of CRF1 or V1b receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression

Richard Alonso, Guy Griebel, G Pavone et al. · Molecular Psychiatry · 2003 · 309 citations

Medicine, Neurobiology, Neuroscience +14

Vasopressin cells in the medial amygdala of the rat project to the lateral septum and ventral hippocampus

A. R. Caffé, F.W. van Leeuwen, P.G.M. Luiten · The Journal of Comparative Neurology · 1987 · 290 citations

Medicine, Neurobiology, Neuroscience +12

Characterization of (2 S,4 R)-1-[5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1 H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a Selective and Orally Active Vasopressin V1b Receptor Antagonist

Claudine Serradeil‐Le Gal, Jean Wagnon, Jacques Simiand et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 210 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Clinical role of brain-derived neurotropic factor in mood disorders

Kenji Hashimoto · Medical Entomology and Zoology · 2004 · 183 citations

Life Sciences, Neurobiology, Neuroscience +14