The p53-independent induction of apoptosis in breast cancer cells in response to proteasome inhibitor bortezomib

Hsp27 negatively regulates cell death by interacting with cytochrome c

Jean‐Marie Bruey, Cécile Ducasse, Philippe Bonniaud et al. · Nature Cell Biology · 2000 · 982 citations

Life Sciences, Cell Biology, Molecular Biology +14

Mouse 4T1 Breast Tumor Model

Beth A. Pulaski, Suzanne Ostrand‐Rosenberg · Current Protocols in Immunology · 2000 · 910 citations

Medicine, Oncology, Surgery +17

In vivo ubiquitination and proteasome-mediated degradation of p53(1).

Carl G. Maki, J M Huibregtse, Peter M. Howley · PubMed · 1996 · 649 citations

Life Sciences, Cell Biology, Molecular Biology +15

p53-dependent Induction of Apoptosis by Proteasome Inhibitors

Ulisses Gazos Lopes, Péter Erhardt, Ryoji Yao et al. · Journal of Biological Chemistry · 1997 · 474 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status

Patricia Pérez‐Galán, Gaël Roué, Neus Villamor et al. · Blood · 2005 · 467 citations · Full text

Life Sciences, Molecular Biology, Oncology +17