Enantiomeric d4T analogues and their structural determination

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

Hiroaki Mitsuya, Kent J. Weinhold, P A Furman et al. · Proceedings of the National Academy of Sciences · 1985 · 1.8K citations · Full text

Immunology, Bw A509u, Cytopathic Effect +16

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.

P A Furman, James A. Fyfe, M H St Clair et al. · Proceedings of the National Academy of Sciences · 1986 · 1.3K citations · Full text

Viral Replication, Thymidine Analog, Immunology +18

Initial studies on the cellular pharmacology of 2′,3′-dideoxycytidine, an inhibitor of HTLV-III infectivity

David A. Cooney, Maha Dalal, Hiroaki Mitsuya et al. · Biochemical Pharmacology · 1986 · 322 citations

Medicine, Htlv-iii Infectivity, Antiviral Drug Development +8

Potent and selective in vitro activity of 3' -deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus

Tai‐Shun Lin, Raymond F. Schinazi, William H. Prusoff · Biochemical Pharmacology · 1987 · 261 citations

Medicinal Chemistry, Antiviral Compound, Biochemistry +11

(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro

Jonathon Alexis Coates, N. Cammack, H J Jenkinson et al. · Antimicrobial Agents and Chemotherapy · 1992 · 240 citations · Full text

Immunology, Pharmacotherapy, Antiviral Drug +16