Radiotherapy-Induced Anti-Tumor Immunity Contributes to the Therapeutic Efficacy of Irradiation and Can Be Augmented by CTLA-4 Blockade in a Mouse Model - Concepedia

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Radiotherapy-Induced Anti-Tumor Immunity Contributes to the Therapeutic Efficacy of Irradiation and Can Be Augmented by CTLA-4 Blockade in a Mouse Model

DOI Full Paper Access

122

Citations

16

References

2014

Year

Yuya Yoshimoto, Yoshiyuki Suzuki, Kousaku Mimura, Ken Ando, Takahiro Oike, Hiro Sato, Noriyuki Okonogi, Takanori Maruyama, Shinichiro Izawa, Shin‐ei Noda,

Abstract

Our results indicate that tumor-specific immune responses play an important role in the therapeutic efficacy of irradiation. Immunomodulation, including CTLA-4 blockade, may be a promising treatment in combination with radiotherapy.

References

	Year	Citations

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