Concepedia

Hypermethylation of the CDKN2/p16INK4A Promotor in Thyroid Carcinogenesis

Carsten Boltze, Stephan Zack, Claudia Quednow, Silke Bettge, Albert Roessner, Regine Schneider‐Stock

Pathology - Research and Practice · 2003 · 55 citations · 16 references

DOI

Concepts

References

16

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

Manuel Serrano, Gregory J. Hannon, David Beach · Nature · 1993 · 3.7K citations

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A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types

Alexander Kamb, Nelleke A. Gruis, Jane Weaver-Feldhaus et al. · Science · 1994 · 2.8K citations

, , +17

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

Adrian Merlo, James G. Herman, Li Mao et al. · Nature Medicine · 1995 · 2K citations

, , +17

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.

James G. Herman, Adrian Merlo, Li Mao et al. · PubMed · 1995 · 1.4K citations

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Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing.

Mirella Gonzalez‐Zulueta, Christina M. Bender, A S Yang et al. · PubMed · 1995 · 712 citations

, , +17