Development of scintillation-proximity assays for alpha adrenoceptors

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

A STUDY OF THE ADRENOTROPIC RECEPTORS

Raymond P. Ahlquist · American Journal of Physiology-Legacy Content · 1948 · 2.9K citations

Life Sciences, Pharmacology, Physiology +8

Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning.

Dan Bylund, Howard S. Blaxall, L J Iversen et al. · Molecular Pharmacology · 1992 · 208 citations · Full text

Medicine, Biochemistry, Pharmacology +13

Scintillation proximity radioimmunoassay utilizing 125I-labeled ligands.

Sidney Udenfriend, Louise Gerber, L Brink et al. · Proceedings of the National Academy of Sciences · 1985 · 80 citations · Full text

Engineering, Pharmacology, Biosensors +7

Structure activity relationships of a series of buspirone analogs at alpha-1 adrenoceptors: further evidence that rat aorta alpha-1 adrenoceptors are of the alpha-1D-subtype.

D L Saussy, Aaron S. Goetz, Kennedy L. Queen et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 78 citations

Medicine, Medicinal Chemistry, Pharmacology +15