Concepedia

TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation

Betty Lamothe, William K. Webster, Ambily Gopinathan, Arnaud Besse, Alejandro D. Campos, Bryant G. Darnay

Biochemical and Biophysical Research Communications · 2007 · 129 citations · 12 references

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Concepts

References

12

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

Mark Lomaga, Wen‐Chen Yeh, Ildiko Sarosi et al. · Genes & Development · 1999 · 1.3K citations · Full text

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TAB2 and TAB3 Activate the NF-κB Pathway through Binding to Polyubiquitin Chains

Atsuhiro Kanayama, Rashu B. Seth, Lijun Sun et al. · Molecular Cell · 2004 · 869 citations · Full text

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Distinct molecular mechanism for initiating TRAF6 signalling

Hong Ye, Joseph R. Arron, Betty Lamothe et al. · Nature · 2002 · 659 citations

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Severe osteopetrosis, defective interleukin‐1 signalling and lymph node organogenesis in <i>TRAF6</i>‐deficient mice

Asuka Naito, Sakura Azuma, Sakae Tanaka et al. · Genes to Cells · 1999 · 638 citations · Full text

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Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation

Chuan-Jin Wu, Dietrich B. Conze, Tao Li et al. · Nature Cell Biology · 2006 · 599 citations

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