Overexpression of SOX2 promotes migration, invasion, and epithelial-mesenchymal transition through the Wnt/β-catenin pathway in laryngeal cancer Hep-2 cells

Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

Thomas Brabletz, Andreas Jung, Simone Reu et al. · Proceedings of the National Academy of Sciences · 2001 · 1K citations · Full text

Medicine, Cell Biology, Oncology +14

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

Adam J. Bass, Hideo Watanabe, Craig H. Mermel et al. · Nature Genetics · 2009 · 952 citations · Full text

Medicine, Molecular Biology, Oncology +14

<i>SOX2</i> Silencing in Glioblastoma Tumor-Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity

Rosaria Gangemi, Fabrizio Griffero, Daniela Marubbi et al. · Stem Cells · 2008 · 572 citations · Full text

Medicine, Cell Biology, Oncology +14

The Molecular Mechanism Governing the Oncogenic Potential of SOX2 in Breast Cancer

Yupeng Chen, Lei Shi, Lirong Zhang et al. · Journal of Biological Chemistry · 2008 · 361 citations · Full text

Medicine, Molecular Biology, Oncology +17

Evidence That SOX2 Overexpression Is Oncogenic in the Lung

Yun Lu, Christopher R. Futtner, Jason R. Rock et al. · PLoS ONE · 2010 · 216 citations · Full text

Medicine, Cell Biology, Oncology +17