Long-Term Compliance with Estrogen Replacement Therapy in Surgical Postmenopausal Women: Benefits to Bone and Analysis of Factors Associated with Discontinuation

Abstract

Long-term ERT may have a protective effect against bone loss in surgically postmenopausal women; however, two thirds of treated patients discontinued therapy after 5 years and 43% of them presented a negative balance on bone mass in one or more bone density assessments. For this reason, enhancing compliance and monitoring treatment are mandatory.