Folate deficiency enhances the inflammatory response of macrophages

Transposable Elements: Targets for Early Nutritional Effects on Epigenetic Gene Regulation

Robert A. Waterland, Randy L. Jirtle · Molecular and Cellular Biology · 2003 · 2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Targeting C-reactive protein for the treatment of cardiovascular disease

Mark B. Pepys, Gideon M. Hirschfield, Glenys A. Tennent et al. · Nature · 2006 · 676 citations · Full text

Medicine, Cardiology, Pharmacology +14

Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease.

Leo A. J. Kluijtmans, Lambertus P. van den Heuvel, G. H. J. Boers et al. · PubMed · 1996 · 660 citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition

Zhuo Chen · Human Molecular Genetics · 2001 · 618 citations

Life Sciences, Genetics, Molecular Genetics +15

Diet, Methyl Donors and DNA Methylation: Interactions between Dietary Folate, Methionine and Choline

Mihai D. Niculescu, Steven H. Zeisel · Journal of Nutrition · 2002 · 544 citations

Life Sciences, Genetics, Nutritional Sciences +15