Science · 1966 · 48 citations · 21 references
Life SciencesMolecular BiologyPathologyHistologyMolecular VirologyVirologyAnimal VirusesOncogenic VirusesViral InfectionsVirus MorphologyVirus PurificationVirus StructureCell Line IsolationDensity Gradient FiltrationElectron Microscopy-based Virus ClassificationProteolytic Enzyme ActivityPurificationStructural Virology
The virus in the EB-3 cell line derived from a Burkitt lymphoma was partially purified by digestion with proteolytic enzyme and by density-gradient centrifugation on potassium tartrate. Electron microscope studies of both sectioned and negatively stained samples suggest that the virus belongs to the herpes-virus group, although the exact number of capsomeres was not unequivocally established.
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The structure of viruses of the papilloma-polyoma type
J.T. Finch, A. Klug · Journal of Molecular Biology · 1965 · 161 citations