Archiv der Pharmazie · 2007 · 33 citations · 11 references
Combinatorial ChemistryMedicinal ChemistrySynthesized CompoundsDerivative (Chemistry)Anticancer ActivitiesBiochemistryNatural SciencesMedicineOrganic ChemistryMulti-step ProcessHeterocycle ChemistryPharmacologyPharmaceutical ChemistryDrug Discovery
Some novel substituted-3-{[(1E)-(substituted-2-furyl)-methylene]amino}quinazolin-4(3H)-one (5, 6, 7) a-f were synthesized by a multi-step process. These synthesized compounds are characterized by various spectroscopic techniques and evaluated for their antitubercular and anticancer activities. Biological activity indicated that some of the title compounds are potent antitubercular and anticancer agents.
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Mann‐Jen Hour, Li‐Jiau Huang, Sheng‐Chu Kuo et al. · Journal of Medicinal Chemistry · 2000 · 404 citations · Full text
Pharmaceutical Science, Chemoprevention Strategy, Organic Chemistry +18
Jack B. Jiang, David P. Hesson, Betsy A. Dusak et al. · Journal of Medicinal Chemistry · 1990 · 261 citations
Tumor Biology, Medicinal Chemistry, Antimitotic Anticancer Agents +14