Synthesis, Antitubercular and Anticancer Activities of Substituted Furyl‐quinazolin‐3(4<i>H</i>)‐ones

Nulgulmnalli Manjunathiah Raghavendra, Parameshwaran Thampi, Purvarga Mattada Gurubasavarajaswamy, Dharmarajan Sriram

Archiv der Pharmazie · 2007 · 33 citations · 11 references

Concepts

Abstract

Some novel substituted-3-{[(1E)-(substituted-2-furyl)-methylene]amino}quinazolin-4(3H)-one (5, 6, 7) a-f were synthesized by a multi-step process. These synthesized compounds are characterized by various spectroscopic techniques and evaluated for their antitubercular and anticancer activities. Biological activity indicated that some of the title compounds are potent antitubercular and anticancer agents.

References

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