Mann-Jen Hour

Antitumor Agents. Part 204: Synthesis and Biological Evaluation of Substituted 2-Aryl Quinazolinones

Yi Xia, Zheng-Yu Yang, Mann-Jen Hour et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 203 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

MJ-29 Inhibits Tubulin Polymerization, Induces Mitotic Arrest, and Triggers Apoptosis via Cyclin-Dependent Kinase 1-Mediated Bcl-2 Phosphorylation in Human Leukemia U937 Cells

Jai‐Sing Yang, Mann-Jen Hour, Wen-Wen Huang et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 92 citations

Life Sciences, Cell Biology, Oncology +17

Novel Quinazolinone MJ-29 Triggers Endoplasmic Reticulum Stress and Intrinsic Apoptosis in Murine Leukemia WEHI-3 Cells and Inhibits Leukemic Mice

Chi‐Cheng Lu, Jai‐Sing Yang, Jo-Hua Chiang et al. · PLoS ONE · 2012 · 63 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Photodynamic activity of aloe-emodin induces resensitization of lung cancer cells to anoikis

Hong-Zin Lee, Wen-Hui Yang, Mann-Jen Hour et al. · European Journal of Pharmacology · 2010 · 51 citations

Medicine, Oncology, Pharmacology +13

Newly synthesized quinazolinone HMJ-38 suppresses angiogenetic responses and triggers human umbilical vein endothelial cell apoptosis through p53-modulated Fas/death receptor signaling

Jo‐Hua Chiang, Jai‐Sing Yang, Chi‐Cheng Lu et al. · Toxicology and Applied Pharmacology · 2013 · 47 citations

Life Sciences, Cell Biology, Pharmacology +14