Is the formation of R-ibuprofenyl-adenylate the first stereoselective step of chiral inversion?

ACYL ADENYLATES: AN ENZYMATIC MECHANISM OF ACETATE ACTIVATION

Paul Berg, With the technical assistance of Georgia Newton · Journal of Biological Chemistry · 1956 · 357 citations · Full text

Life Sciences, Biochemistry, Enzyme Mechanism +7

The Chemical Synthesis of Amino Acyl Adenylates

Paul Berg · Journal of Biological Chemistry · 1958 · 132 citations · Full text

Life Sciences, Biochemistry, Chemistry +11

Stereoselective high-performance liquid chromatographic determination of ketoprofen, ibuprofen and fenoprofen in plasma using a chiral α1-acid glycoprotein column

S. Menzel-Soglowek, Kay Brune · Journal of Chromatography B Biomedical Sciences and Applications · 1990 · 83 citations

Pharmacy, Pharmacokinetics, Pharmacology +12

Purification and characterization of novel “2-arylpropionyl-CoA epimerases” from rat liver cytosol and mitochondria.

W.‐R. SHIEH · Journal of Biological Chemistry · 1993 · 74 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

OPTICAL ISOMERIZATION MECHANISM OF R (-)-HYDRATROPIC ACID DERIVATIVES

Yutaka Nakamura, Toshiro Yamaguchi, Shirō Takahashi et al. · Journal of Pharmacobio-Dynamics · 1981 · 71 citations

Natural Sciences, Chemistry, Medicinal Chemistry +4