Concepedia

Inversion Of Configuration

Inversion of Configuration is a stereochemical phenomenon in which the spatial arrangement of atoms around a chiral center is reversed during a nucleophilic substitution reaction, specifically characterizing the Walden inversion mechanism in which the reacting center undergoes a backside attack leading to an umbrella-like flipping of molecular geometry.

73

Publications

2.4K

Citations

243

Authors

79

Institutions

Publications per year

2017–2026

7

Variants

Walden Inversion

Parents

Publications

73

Effect of structure on the rate of pyramidal inversion of acyclic phosphines

Raymond D. Baechler, Kurt Mislow · Journal of the American Chemical Society · 1970 · 218 citations

, , +6

Dinuclear Catecholate Helicates:  Their Inversion Mechanism

Berthold Kersting, Michel Meyer, Ryan E. Powers et al. · Journal of the American Chemical Society · 1996 · 141 citations

, , +7

Rearrangement Reactions in Dinuclear Triple Helicates<sup>1</sup>

Michel Meyer, Berthold Kersting, Ryan E. Powers et al. · Inorganic Chemistry · 1997 · 123 citations

, , +16

Chiroptical generation and inversion during the mirror-symmetry-breaking aggregation of dialkylpolysilanes due to limonene chirality

Yoko Nakano, Fumiko Ichiyanagi, Masanobu Naito et al. · Chemical Communications · 2012 · 91 citations

, , +8

Bicyclic Structures Prohibiting the Walden Inversion. Replacement Reactions in 1-Substituted 1-Apocamphanes

Paul D. Bartlett, Lawrence H. Knox · Journal of the American Chemical Society · 1939 · 82 citations

, , +13

1–5 of 73

Authors

243

  1. PD
    Paul D. Bartlett

    University of Bristol, United Kingdom

    3 publications · 129 citations

    3

    h-index

  2. HB
    Hagan Bayley

    University of Oxford, United Kingdom

    2 publications · 42 citations

    2

    h-index

  3. KN
    Kenneth N. Raymond

    University of California, Berkeley, United States

    2 publications · 264 citations

    2

    h-index

  4. RE
    Robert E. Carter

    University of Louisville, United States

    2 publications · 65 citations

    2

    h-index

  5. SS
    Seong‐Ho Shin

    Lawrence Berkeley National Laboratory, United States

    2 publications · 42 citations

    2

    h-index

1–5 of 243

Institutions

79

  1. University of California, Berkeley

    Berkeley, United States

    5 h-index

    14 publications

    1.1K citations

  2. Lund University

    Lund, Sweden

    2 h-index

    4 publications

    130 citations

  3. University of Oxford

    Oxford, United Kingdom

    2 h-index

    8 publications

    168 citations

  4. Université Paris Cité

    Paris, France

    2 h-index

    8 publications

    145 citations

  5. Lawrence Berkeley National Laboratory

    Berkeley, United States

    2 h-index

    2 publications

    42 citations

  6. Southern Utah University

    Cedar City, United States

    2 h-index

    2 publications

    42 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    8 publications

    145 citations

  8. Kyoto University

    Kyoto, Japan

    2 h-index

    5 publications

    69 citations

1–8 of 79

Venues

  1. Journal of the American Chemical Society

    JACS · 11 publications · 684 citations

    11

    h-index

  2. The Journal of Organic Chemistry

    JOC · 6 publications · 152 citations

    6

    h-index

  3. Tetrahedron Letters

    6 publications · 128 citations

    6

    h-index

  4. Organic Letters

    OL · 3 publications · 89 citations

    3

    h-index

  5. Angewandte Chemie International Edition

    3 publications · 105 citations

    3

    h-index

1–5