A Zinc Site in the C-Terminal Domain of RAG1 Is Essential for DNA Cleavage Activity

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

J. Fraser McBlane, Dik C. van Gent, Dale A. Ramsden et al. · Cell · 1995 · 709 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

RAG1 Core and V(D)J Recombination Signal Sequences Were Derived from Transib Transposons

Jerzy Jurka · PLoS Biology · 2005 · 495 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Structure of thermolysin refined at 1.6 Å resolution

Michael Holmes, Brian W. Matthews · Journal of Molecular Biology · 1982 · 444 citations

Life Sciences, Biochemistry, Biophysics +9

Stimulation of V(D)J cleavage by high mobility group proteins

Dik C. van Gent, Kevin Hiom, Tanya T. Paull et al. · The EMBO Journal · 1997 · 257 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +6

The Homeodomain Region of Rag-1 Reveals the Parallel Mechanisms of Bacterial and V(D)J Recombination

Eugenia Spanopoulou, Florina Zaitseva, Fu-Hou Wang et al. · Cell · 1996 · 223 citations · Full text

Life Sciences, Genetics, Molecular Biology +15