A stereocontrolled synthesis of (−)-bestatin from an acyclic allylamine by iodocyclocarbamation

Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes.

HAMAO UMEZAWA, TAKAAKI AOYAGI, Suda Hiroyuki et al. · The Journal of Antibiotics · 1976 · 721 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7

Stereocontrol in the synthesis of acyclic systems: applications to natural product synthesis

Paul A. Bartlett · Tetrahedron · 1980 · 506 citations

Pharmacy, Chemistry, Medicinal Chemistry +13

Stereocontrolled synthesis of (+)-negamycin from an acyclic homoallylamine by 1,3-asymmetric induction

Yi Fong Wang, Toshio Izawa, Susumu Kobayashi et al. · Journal of the American Chemical Society · 1982 · 281 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

Stereoselective epoxidation of acyclic olefinic carboxylic acids via iodolactonization

Paul A. Bartlett, Joel Myerson · Journal of the American Chemical Society · 1978 · 214 citations

Natural Sciences, Chemistry, Analytical Chemistry +10

Stereo and regioselective openings of chiral 2,3-epoxy alcohols. Versatile routes to optically pure natural products and drugs. Unusual kinetic resolutions

K. Barry Sharpless, Carl H. Behrens, Tsutomu Katsuki et al. · Pure and Applied Chemistry · 1983 · 213 citations

Pharmacy, Chemistry, Medicinal Chemistry +5