Concepedia

Monoclonal antibody targeting of methotrexate (MTX) against MTX-resistant tumour cell lines

Karen Affleck, MJ Embleton

British Journal of Cancer · 1992 · 12 citations · 32 references

DOIFull text

Open access

Concepts

References

32

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

S Ohkuma, Brian D. Poole · Proceedings of the National Academy of Sciences · 1978 · 2.2K citations · Full text

, , +17

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

F W Alt, Rodney E. Kellems, Joseph R. Bertino et al. · Journal of Biological Chemistry · 1978 · 980 citations · Full text

, , +4

Inhibition of the Lysosomal Pathway of Protein Degradation in Isolated Rat Hepatocytes by Ammonia, Methylamine, Chloroquine and Leupeptin

Per O. Seglen, Bjørn Grinde, Anne E. Solheim · European Journal of Biochemistry · 1979 · 470 citations · Full text

, , +10

Antibody directed enzymes revive anti-cancer prodrugs concept

K D Bagshawe · British Journal of Cancer · 1987 · 278 citations · Full text

, , +12

Relative frequency and kinetic properties of transport-defective phenotypes among methotrexate-resistant L1210 clonal cell lines derived in vivo.

F. M. Sirotnak, D. M. Moccio, L. E. Kelleher et al. · PubMed · 1981 · 189 citations

, , +9