Dual role of anti-TNF therapy: Enhancement of TCR-mediated T cell activation in peripheral blood and inhibition of inflammation in target tissues

Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2

Bob W. van Oosten, Frederik Barkhof, L. Truyen et al. · Neurology · 1996 · 733 citations

Life Sciences, Immunology, Neurology +17

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

Lisa C. Zaba, Irma Cardinale, Patricia Gilleaudeau et al. · The Journal of Experimental Medicine · 2007 · 668 citations · Full text

Medicine, Dermatology, Immunology +13

Tumor necrosis factor α antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohn's ileocolitis

Filip J. Baert, Geert D’Haens, Marc Peeters et al. · Gastroenterology · 1999 · 467 citations · Full text

Life Sciences, Immunology, Pathology +12

Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor α blockade in patients with rheumatoid arthritis

Peter C. Taylor, A. Michael Peters, Ewa Paleolog et al. · Arthritis & Rheumatism · 2000 · 401 citations

Life Sciences, Clinical Sciences, Immunology +17

TNF Inhibition Rapidly Down-Regulates Multiple Proinflammatory Pathways in Psoriasis Plaques

Alice B. Gottlieb, Francesca Chamian, Salman Masud et al. · The Journal of Immunology · 2005 · 371 citations · Full text

Life Sciences, Dermatology, Immunology +17