Concepedia

Gene–environment interaction demonstrates the vulnerability of the embryonic heart

Victoria C. O׳Reilly, Kylie Lopes Floro, Hongjun Shi, Bogdan E. Chapman, Jost I. Preis, Alexander C. James, Gavin Chapman, Richard P. Harvey, Randall S. Johnson, Stuart M. Grieve,

Developmental Biology · 2014 · 16 citations · 41 references

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References

41

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

G L Wang, Bing‐Hua Jiang, E A Rue et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

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Cellular and developmental control of O<sub>2</sub> homeostasis by hypoxia-inducible factor 1α

Narayan V. Iyer, Lori E. Kotch, Faton Agani et al. · Genes & Development · 1998 · 2.5K citations · Full text

, , +16

HIF‐1α is required for solid tumor formation and embryonic vascularization

Heather E. Ryan · The EMBO Journal · 1998 · 1.6K citations · Full text

, , +14

Asparagine Hydroxylation of the HIF Transactivation Domain: A Hypoxic Switch

David Lando, Daniel J. Peet, Dean A. Whelan et al. · Science · 2002 · 1.5K citations

, , +14

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

David Lando, Daniel J. Peet, Jeffrey J. Gorman et al. · Genes & Development · 2002 · 1.5K citations · Full text

, , +17