High prevalence of CYP2D6*41 (G2988A) allele in Saudi Arabians

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

Christoph Sachse, Jürgen Brockmöller, Steffen Bauer et al. · PubMed · 1997 · 979 citations

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Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation.

Inger Johansson, Mikael Oscarson, Qun‐Ying Yue et al. · Molecular Pharmacology · 1994 · 430 citations

Medicine, Genetics, Molecular Genetics +16

CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure

Johanna Sistonen, Antti Sajantila, Óscar Lao et al. · Pharmacogenetics and Genomics · 2007 · 400 citations

Life Sciences, Genetics, Pharmacology +16

Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles.

Eleni Aklillu, Irene Persson, Leif Bertilsson et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 396 citations

Life Sciences, Genetics, Pharmacology +17

Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution

Delphine Marez, Maryline Legrand, N. Sabbagh et al. · Pharmacogenetics · 1997 · 378 citations

Life Sciences, Genetics, Molecular Genetics +15