Concepedia

Inhibition of NAMPT pathway by FK866 activates the function of p53 in HEK293T cells

Basant Kumar Thakur, Tino Dittrich, Annette Becker, Yannick Lippka, Divakarvel Selvakumar, Jan‐Henning Klusmann, Dirk Reinhardt, Karl Welte

Biochemical and Biophysical Research Communications · 2012 · 40 citations · 17 references

DOI

Concepts

References

17

hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

Homayoun Vaziri, Scott Dessain, Elinor Ng Eaton et al. · Cell · 2001 · 2.6K citations · Full text

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Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

Jianyuan Luo, Anatoly Nikolaev, Shin‐ichiro Imai et al. · Cell · 2001 · 2.1K citations · Full text

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Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1

Kevin J. Bitterman, Rozalyn M. Anderson, Haim Cohen et al. · Journal of Biological Chemistry · 2002 · 998 citations · Full text

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The NAD Biosynthesis Pathway Mediated by Nicotinamide Phosphoribosyltransferase Regulates Sir2 Activity in Mammalian Cells

Javier R. Revollo, Andrew A. Grimm, Shin‐ichiro Imai · Journal of Biological Chemistry · 2004 · 993 citations · Full text

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Human SIR2 deacetylates p53 and antagonizes PML/p53‐induced cellular senescence

The EMBO Journal · 2002 · 851 citations · Full text

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