Concepedia

LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis

Pekka Katajisto, Kari Vaahtomeri, Niklas Ekman, Eeva Ventelä, Ari Ristimäki, Nabeel Bardeesy, Robert Feil, Ronald A. DePinho, Tomi P. Mäkelä

Nature Genetics · 2008 · 114 citations · 23 references

DOI

Concepts

References

23

A serine/threonine kinase gene defective in Peutz–Jeghers syndrome

Akseli Hemminki, David Markie, Ian Tomlinson et al. · Nature · 1998 · 1.6K citations

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Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade

Simon A. Hawley, Jérôme Boudeau, Jennifer L. Reid et al. · Journal of Biology · 2003 · 1.6K citations · Full text

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TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia

Neil A. Bhowmick, Anna Chytil, David Plieth et al. · Science · 2004 · 1.4K citations

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LKB1 modulates lung cancer differentiation and metastasis

Hongbin Ji, Matthew R. Ramsey, D. Neil Hayes et al. · Nature · 2007 · 1.1K citations

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The LKB1 tumor suppressor negatively regulates mTOR signaling

Reuben J. Shaw, Nabeel Bardeesy, Brendan D. Manning et al. · Cancer Cell · 2004 · 1.1K citations · Full text

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