Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2

Pipsa Saharinen, Katja Kerkelä, Niklas Ekman, +6

The Journal of Cell Biology

Signal Transduction PathwaysEndothelial CellsImmunologyCellular PhysiologyAngiogenesis +14

Etk/Bmx Transactivates Vascular Endothelial Growth Factor 2 and Recruits Phosphatidylinositol 3-Kinase to Mediate the Tumor Necrosis Factor-induced Angiogenic Pathway

Rong Zhang, Yingqian Xu, Niklas Ekman, +4

Journal of Biological Chemistry

LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis

Pekka Katajisto, Kari Vaahtomeri, Niklas Ekman, +6

Nature Genetics

Signal TransductionSignaling PathwayCell RegulationReceptor Tyrosine KinaseImmunology +7

The Bmx Tyrosine Kinase Induces Activation of the Stat Signaling Pathway, Which Is Specifically Inhibited by Protein Kinase Cδ

Pipsa Saharinen, Niklas Ekman, Krista Sarvas, +3

Blood

Bmx Tyrosine Kinase Has a Redundant Function Downstream of Angiopoietin and Vascular Endothelial Growth Factor Receptors in Arterial Endothelium

Iiro Rajantie, Niklas Ekman, Kristiina Iljin, +7

Molecular and Cellular Biology

<i>Bmx</i> Tyrosine Kinase Is Specifically Expressed in the Endocardium and the Endothelium of Large Arteries

Niklas Ekman, Athina Lymboussaki, Imre Västrik, +3

Circulation

p130Cas Couples the Tyrosine Kinase Bmx/Etk with Regulation of the Actin Cytoskeleton and Cell Migration

Yama Abassi, Marko Rehn, Niklas Ekman, +2

Journal of Biological Chemistry

LKB1 in endothelial cells is required for angiogenesis and TGFβ-mediated vascular smooth muscle cell recruitment

Anou Londesborough, Kari Vaahtomeri, Marianne Tiainen, +4

Development

Endothelial CellsCell DeathCellular PhysiologyTumor BiologyVascular Disruption +14

The Bmx tyrosine kinase is activated by IL-3 and G-CSF in a PI-3K dependent manner

Niklas Ekman, Elena Arighi, Iiro Rajantie, +4

Oncogene

InflammationCytokineSignal TransductionCell RegulationSignaling Pathway +9

Bmx Tyrosine Kinase Transgene Induces Skin Hyperplasia, Inflammatory Angiogenesis, and Accelerated Wound Healing

Karri Paavonen, Niklas Ekman, Maria Wirzenius, +3

Molecular Biology of the Cell

ImmunologyInflammatory AngiogenesisCell ProliferationAccelerated Wound HealingDermatology +17