Development of a Comprehensive Panel of Antibodies against the Major Xenobiotic Metabolising Forms of Cytochrome P450 in Humans

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

Life Sciences, Biochemistry, Chemistry +8

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

Medicine, Biochemistry, Pharmacology +15

Genetic Polymorphisms in the 5′-Flanking Region Change Transcriptional Regulation of the Human Cytochrome P450IIE1 Gene1

Shin‐ichi Hayashi, Junko Watanabe, Kaname Kawajiri · The Journal of Biochemistry · 1991 · 677 citations

Life Sciences, Genetics, Molecular Genetics +14

A simple and sensitive assay of 7-ethoxycoumarin deethylation

Antero Aitio · Analytical Biochemistry · 1978 · 611 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

Thomas Kronbach, Daniel Mathys, Makoto Umeno et al. · Molecular Pharmacology · 1989 · 535 citations

Medicine, Pharmacology, Biochemical Pharmacology +15