Concepedia

Antitumor agents—CLI. Bis(helenalinyl)glutarate and bis(isoalantodiol-B)glutarate, potent inhibitors of human DNA topoisomerase II

Chung-Hsiung Chen, Liming Yang, Thomas Tung-Ying Lee, Ya-Ching Shen, De-Cheng Zhang, De-Ji Pan, Andrew T. McPhail, Donald R. McPhail, Su-Yin Liu, De-Hua Li,

Bioorganic & Medicinal Chemistry · 1994 · 13 citations · 27 references

DOI

Concepts

References

27

<i>International Tables for X-ray Crystallography</i>

Acta Crystallographica Section B · 1976 · 14.2K citations · Full text

, , +11

Anti-cancer Drug Design

M SISSAOUI · Archives of Clinical Microbiology · 2018 · 1.4K citations

Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

K M Tewey, G L Chen, Eric M. Nelson et al. · Journal of Biological Chemistry · 1984 · 888 citations · Full text

, , +14

DNA topoisomerase II is required at the time of mitosis in yeast

Christian Holm, Takashi Goto, Jingjing Wang et al. · Cell · 1985 · 762 citations

, , +11

Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

G L Chen, Thomas C. Rowe, Brian Halligan et al. · Journal of Biological Chemistry · 1984 · 499 citations · Full text

, , +11