The effect of a new immunosuppressive agent, FK-506, on xenogeneic neural transplantation in rodents

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics.

Toru Kino, Hiroshi Hatanaka, MICHISANE HASHIMOTO et al. · The Journal of Antibiotics · 1987 · 1.2K citations · Full text

Medicine, Biochemistry, Pharmacology +10

FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro.

Toru Kino, Hiroshi Hatanaka, Susumu Miyata et al. · The Journal of Antibiotics · 1987 · 1.2K citations · Full text

Medicine, Immunology, Pharmacology +9

Grafts of Fetal Dopamine Neurons Survive and Improve Motor Function in Parkinson's Disease

Olle Lindvall, Patrik Brundin, Håkan Widner et al. · Science · 1990 · 1.2K citations

Life Sciences, Neurology, Neuroscience +17

Immunologically Privileged Sites

Clyde F. Barker, R. E. Billingham · Advances in immunology · 1978 · 812 citations

The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes.

Michael J. Tocci, D A Matkovich, Kathy Collier et al. · The Journal of Immunology · 1989 · 670 citations

Life Sciences, Immunology, Pharmacology +16