C. elegans SGK-1 Is the Critical Component in the Akt/PKB Kinase Complex to Control Stress Response and Life Span

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

C C Mello, James M. Kramer, Dan T. Stinchcomb et al. · The EMBO Journal · 1991 · 3.2K citations · Full text

Efficient Gene Transfer, Developmental Biology, Genetics +8

Mechanism of activation of protein kinase B by insulin and IGF-1.

Dario R. Alessi, Mirjana Andjelković, B. Caudwell et al. · The EMBO Journal · 1996 · 3K citations · Full text

Molecular Physiology, Signal Transduction, Signaling Pathway +9

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

Coleen T. Murphy, Steven A. McCarroll, Cornelia I. Bargmann et al. · Nature · 2003 · 2.3K citations

Lifespan Extension, Developmental Biology, Molecular Physiology +9

<i>daf-2</i> , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in <i>Caenorhabditis elegans</i>

Koutarou D. Kimura, Heidi A. Tissenbaum, Yanxia Liu et al. · Science · 1997 · 2.3K citations

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

Scott Ogg, Suzanne Paradis, S Gottlieb et al. · Nature · 1997 · 1.9K citations

Systems Biology, Genetics, Gene Regulation +7