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Adiponectin Enhances Insulin Sensitivity by Increasing Hepatic IRS-2 Expression via a Macrophage-Derived IL-6-Dependent Pathway

Motoharu Awazawa, Kohjiro Ueki, Kazunori Inabe, Toshimasa Yamauchi, Naoto Kubota, Kazuma Kaneko, Masatoshi Kobayashi, Aya Iwane, Takayoshi Sasako, Yukiko Okazaki,

Cell Metabolism · 2011 · 274 citations · 48 references

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48

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Toshimasa Yamauchi, Junji Kamon, Hironori Waki et al. · Nature Medicine · 2001 · 4.9K citations

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C-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus

Aruna D. Pradhan · JAMA · 2001 · 4.4K citations

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Toshimasa Yamauchi, Junji Kamon, Yasuhiko Minokoshi et al. · Nature Medicine · 2002 · 4.2K citations

, , +16

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

Toshimasa Yamauchi, Junji Kamon, Yusuke Ito et al. · Nature · 2003 · 3.2K citations

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IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

Gökhan S. Hotamışlıgil, Pascal Peraldi, Adriane I. Budavari et al. · Science · 1996 · 2.6K citations

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