β-Lapachone induces programmed necrosis through the RIP1-PARP-AIF-dependent pathway in human hepatocellular carcinoma SK-Hep1 cells

Identification of RIP1 kinase as a specific cellular target of necrostatins

Alexei Degterev, Junichi Hitomi, Megan Germscheid et al. · Nature Chemical Biology · 2008 · 2K citations · Full text

Reductive Stress, Specific Cellular Target, Signal Transduction +13

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

Jixi Li, Thomas J. McQuade, Ansgar B. Siemer et al. · Cell · 2012 · 1.2K citations · Full text

Inflammation, Alzheimer's Disease, Cell Death +9

Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis)

Zbigniew Darżynkiewicz, Gloria Juan, Xun Li et al. · Cytometry · 1997 · 1.1K citations

Term Cell Necrobiology, Cell Necrobiology, Apoptosis +18

NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of β-Lapachone Cytotoxicity

John J. Pink, Sarah M. Planchon, Colleen Tagliarino et al. · Journal of Biological Chemistry · 2000 · 366 citations · Full text

Identification of a Novel Homotypic Interaction Motif Required for the Phosphorylation of Receptor-interacting Protein (RIP) by RIP3

Xiaoqing Sun, Jianping Yin, Melissa A. Starovasnik et al. · Journal of Biological Chemistry · 2002 · 362 citations · Full text