Concepedia

Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis in colorectal cancer

Michael I. Koukourakis, Alexandra Giatromanolaki, C. Simopoulos, Alexandros Polychronidis, Efthimios Sivridis

Clinical & Experimental Metastasis · 2005 · 234 citations · 29 references

DOI

Concepts

References

29

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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Principles of biochemistry

Biochemical Education · 1978 · 5.1K citations

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Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1.

GL Semenza, Pinchas Roth, Hui‐Yuan Fang et al. · Journal of Biological Chemistry · 1994 · 1.9K citations · Full text

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Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma

Robert J. Motzer, Madhu Mazumdar, Jennifer Bacik et al. · Journal of Clinical Oncology · 1999 · 1.8K citations

, , +17

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

Gregg L. Semenza, Bing‐Hua Jiang, Sandra W. Leung et al. · Journal of Biological Chemistry · 1996 · 1.8K citations · Full text

, , +15