One pot protecting group free synthesis of multifunctional biphenyl methyl-C-β-d-glycosides in aqueous medium

Discovery of Canagliflozin, a Novel <i>C</i>-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus

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T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes.

Akira Oku, Kiichiro Ueta, Kenji Arakawa et al. · Diabetes · 1999 · 253 citations

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The Organic chemistry of sugars

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A convenient, one-step, synthesis of β-C-glycosidic ketones in aqueous media

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Na+-Glucose Cotransporter Inhibitors as Antidiabetics. I. Synthesis and Pharmacological Properties of 4'-Dehydroxyphlorizin Derivatives Based on a New Concept.

Kenji Tsujihara, Mitsuya Hongu, Kunio SAITO et al. · Chemical and Pharmaceutical Bulletin · 1996 · 94 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15