Blocking the ends of transforming DNA enhances gene targeting in Dictyostelium

Current protocols in molecular biology

R.K. Dudley · FEBS Letters · 1988 · 6K citations · Full text

Life Sciences, Molecular Biology, Documentation +10

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

Life Sciences, Developmental Biology, Molecular Biology +12

Transformation of yeast.

A. Hinnen, James Hicks, Gerald R. Fink · Proceedings of the National Academy of Sciences · 1978 · 2.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

Medicine, Genetics, Molecular Genetics +15

Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila

Douglas R. Dorer · Cell · 1994 · 513 citations

Life Sciences, Genetics, Molecular Genetics +16