Concepedia

Asymmetric Synthesis of 4,4-Disubstituted-2-Imidazoli-dinones:  Potent NK<sub>1</sub> Antagonists

Gregory A. Reichard, Carmine N. Stengone, Sunil Paliwal, Ingrid Mergelsberg, Sapna Majmundar, Cheng Wang, Robert L. Tiberi, Andrew T. McPhail, John J. Piwinski, Neng‐Yang Shih

Organic Letters · 2003 · 71 citations · 5 references

DOI

Concepts

Abstract

[structure: see text] A highly efficient and practical synthesis of 4,4-Disubstituted-2-Imidazolidinones utilizing a "self-reproduction of the center of chirality" strategy is described.

References

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