Genistein inhibits aggregation of exogenous amyloid-beta1–40 and alleviates astrogliosis in the hippocampus of rats

The rat brain in stereotaxic coordinates

Miklós Palkovits · Neuropeptides · 1983 · 29K citations

Medicine, Neurobiology, Neuroscience +12

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

Tetsu Akiyama, Junko Ishida, Shizue Nakagawa et al. · Journal of Biological Chemistry · 1987 · 3.7K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Dora Games, David S. Adams, Ree Alessandrini et al. · Nature · 1995 · 2.5K citations

Life Sciences, Neurology, Neuroscience +16

Adult mouse astrocytes degrade amyloid-β in vitro and in situ

Tony Wyss‐Coray, John D. Loike, Thomas C. Brionne et al. · Nature Medicine · 2003 · 898 citations

Life Sciences, Neurobiology, Neuroscience +12

Mice lacking glial fibrillary acidic protein display astrocytes devoid of intermediate filaments but develop and reproduce normally.

Milos Pekny, P. Levéen, Marcela Pekna et al. · The EMBO Journal · 1995 · 335 citations

Medicine, Neurobiology, Neuroscience +14