Chloride-led Disruption of the Intestinal Mucous Layer Impedes <i>Salmonella</i> Invasion: Evidence for an ‘Enteric Tear’ Mechanism

Abstract

These data suggest a role for chloride led fluid secretion in the shedding of the adherent mucous-gel layer, possibly as a rate-limiting innate defence mechanism, and offer evidence for "enteric tears" in intestinal host defence.