The relationship between tumour necrosis factor (TNF)-α promoter and<i>IL12B</i>/<i>IL-23R</i>genes polymorphisms and the efficacy of anti-TNF-α therapy in psoriasis: a case-control study

Abstract

This study identified a relationship between certain TNF-α and IL12B/IL23R polymorphisms and the short-term response to anti-TNF-α drugs. If these results are confirmed, this information will allow for stratified consent with more accurate prediction of response/personalized choice of treatment hierarchy for the patient.