The Novel Function of Nesfatin-1 as an Anti-inflammatory and Antiapoptotic Peptide in Subarachnoid Hemorrhage–Induced Oxidative Brain Damage in Rats

Derya Özsavcı, Mehmet Erşahin, Azize Şener, Özlem Bingöl Özakpınar, Hale Z. Toklu, Dilek Akakın, Göksel Şener, Berrak Ç. Yeğen

Neurosurgery · 2011 · 114 citations · 50 references

Abstract

These findings suggest that nesfatin-1, which appears to have antiapoptotic and anti-inflammatory properties, exerts neuroprotection in SAH-induced injury in rats by inhibiting neutrophil infiltration and subsequent release of inflammatory mediators.

References

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