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Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells. Reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation

Defensive Protein KinaseTumor BiologyHematological MalignancyChemoprevention StrategyArsenic Trioxide CombinationMedicineCancer Cell BiologyCell DeathHuman Leukemia CellsAnti-cancer AgentPharmacologyRadiation OncologyCancer ResearchOxidative Stress