Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels

Federica Chiara, Diego Castellaro, Oriano Marin, +7

PLoS ONE

ApoptosisCell DeathHexokinase Ii DetachmentCellular PhysiologyType Ii Hexokinase +14

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

Anna Pastò, Chiara Bellio, Giorgia Pilotto, +11

Oncotarget

The Mitochondrial Chaperone TRAP1 Promotes Neoplastic Growth by Inhibiting Succinate Dehydrogenase

Marco Sciacovelli, Giulia Guzzo, Virginia Morello, +10

Cell Metabolism

BiologySuccinate DehydrogenaseReductive StressMitochondrial FunctionNatural Sciences +8

Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition

Andrea Rasola, Marco Sciacovelli, Federica Chiara, +3

Proceedings of the National Academy of Sciences

MitophagyChemoprevention StrategyApoptosisErk InhibitionCell Death +20

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer

Jingjing Chen, Ilaria Guccini, Diletta Di Mitri, +27

Nature Genetics

Energy MetabolismBiosynthesisAldehyde DehydrogenaseBiochemistryCompartmentalized Activities +7

Developmental Shift of Cyclophilin D Contribution to Hypoxic-Ischemic Brain Injury

Xiaoyang Wang, Ylva Carlsson, Emy Basso, +9

Journal of Neuroscience

Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death

Daniela Catanzaro, Edoardo Gaude, Genny Orso, +7

Oncotarget

Hexokinase 2 displacement from mitochondria‐associated membranes prompts Ca ²⁺ ‐dependent death of cancer cells

Francesco Ciscato, Riccardo Filadi, Ionica Masgras, +10

EMBO Reports

A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth

Andrea Rasola, Michela Fassetta, Francesca De Bacco, +4

Oncogene

Tumor BiologyMedicineLiver PhysiologyColorectal CancerPathology +7

A flow cytometry assay simultaneously detects independent apoptotic parameters

Andrea Rasola, Massimo Geuna

Cytometry