Soluble Cytokines Can Act as Effective Adjuvants in Plasmid DNA Vaccines Targeting Self Tumor Antigens

Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses.

Eytan Raz, Dennis A. Carson, Suezanne E. Parker et al. · Proceedings of the National Academy of Sciences · 1994 · 545 citations

Veterinary Medicine, Immunology, Infectious Diseases +17

Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization.

Eytan Raz, Helen Tighe, Yukio Sato et al. · Proceedings of the National Academy of Sciences · 1996 · 517 citations

Life Sciences, Immunology, Adaptive Immunity +16

Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines

Zhiquan Xiang, Hildegund C.J. Ertl · Immunity · 1995 · 480 citations · Full text

Life Sciences, Immunology, Infectious Diseases +14

Gene vaccination with naked plasmid DNA: mechanism of CTL priming.

Maripat Corr, D J Lee, Dennis A. Carson et al. · The Journal of Experimental Medicine · 1996 · 478 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients

Keith L. Knutson, Kathy Schiffman, Mary L. Disis · Journal of Clinical Investigation · 2001 · 450 citations · Full text

Life Sciences, Immunology, Oncology +17