Concepedia

Crosstalk between the cGAS DNA Sensor and Beclin-1 Autophagy Protein Shapes Innate Antimicrobial Immune Responses

Qiming Liang, Gil Ju Seo, Youn Jung Choi, Mi‐Jeong Kwak, Jianning Ge, Mary A. Rodgers, Mude Shi, Benjamin J. Leslie, Karl‐Peter Hopfner, Taekjip Ha,

Cell Host & Microbe · 2014 · 344 citations · 26 references

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26

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Lijun Sun, Jiaxi Wu, Fenghe Du et al. · Science · 2012 · 4.8K citations

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Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

Jiaxi Wu, Lijun Sun, Xiang Chen et al. · Science · 2012 · 2.5K citations

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In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker

Noboru Mizushima, Akitsugu Yamamoto, Makoto Matsui et al. · Molecular Biology of the Cell · 2003 · 2.3K citations · Full text

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

Akinori Takaoka, Zhichao Wang, Myoung Kwon Choi et al. · Nature · 2007 · 1.7K citations

, , +14

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Andrea Ablasser, Marion Goldeck, Taner Cavlar et al. · Nature · 2013 · 1.6K citations · Full text

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